Scientists have stated that a new drug that works to reverse ageing could be on the market in just three years. The drug, named nicotinamide mononucleotide (NMN), showed dramatic rejuvenating properties during early experiments that were conducted on ageing mice. Following this initial success, the researchers are hoping to start testing the drug on humans during clinical trials within the next six months.
Lead scientist Professor David Sinclair, from the University of South Wales in Australia and Harvard Medical School in the US, said, “The cells of the old mice were indistinguishable from the young mice, after just one week of treatment. This is the closest we are to a safe and effective anti-ageing drug that’s perhaps only three to five years away from being on the market if the trials go well.”
Accumulated DNA damage is a major driver of natural ageing and a primary cause of cancer. The drug NMN works by boosting the individual’s levels of NAD+, which naturally reduces overtime as the ageing process occurs, and therefore means that the DNA is not repaired efficiently. The new drug therefore helps to repair the damaged DNA. NAD+ has been increasingly sold online as an anti-ageing supplement, after these properties were highlighted. However, there is currently little evidence to show that mere small doses of NAD+ can stop ageing.
Another potential benefit of the drug is currently being examined by NASA, according to recent reports, as it is hoped that it could be an aid in sending astronauts to Mars. The scientists testing the drug believe that there could be potential that NMN could be able to act as a shield against the effects of radiation, so that astronauts are protected during their long journey to the new planet.
The clinical trials are predicted to start at Brigham and Women’s Hospital in Boston, US, later this year.
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